Ceruloplasmin

Ceruloplasmin, is a glycoprotein produced in the liver and transports more than 95 percent of the copper in blood. Copper plays an important role in the body by aiding crucial bodily processes. These include producing energy, forming connective tissue, and helping the central nervous system function. Decreased levels of ceruloplasmin are found in Wilson's Disease, fulminant liver failure, intestinal malabsorption, renal failure resulting in proteinuria, chronic active hepatitis and malnutrition. Elevated levels are found in primary biliary cirrhosis, pregnancy (first trimester), oral contraceptive use and in acute inflammatory conditions since ceruloplasmin is an acute phase reactant.